Recombinant Human MIP-3 alpha / CCL20

Molecule:

CCL20

Synonyms:

Macrophage inflammatory protein 3 alpha, C-C motif chemokine 20, CCL20, Beta-chemokine exodus-1, CC chemokine LARC, small-inducible cytokine A20.

Species:

Human

Cat. No.:

CRH317C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$3,200.00 / Special Price: $2,100.00 BUY

Description:

Macrophage inflammatory protein-3 alpha (MIP-3 α), also called CCL20, is expressed in the liver, lungs, lymph nodes, and peripheral blood lymphocytes. MIP-3 α expression is strongly induced by inflammatory signals, and downregulated by the anti-inflammatory cytokine interleukin 10 (IL-10). MIP-3 α signals through the G protein-coupled receptor CCR6 to function as a chemoattractant to lymphocytes and dendritic cells.

Entrez Symbol:

CCL20

Uniprot Name:

C-C motif chemokine 20

Uniprot ID:

P78556

Data PDF:

CRH317

Source:

E. coli

Molecular Weight:

Monomer, 8 kDa (70 aa)

Formulation:

Lyophilized from a sterile-filtered solution containing 0.1% Trifluoroacetic Acid

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

This product demonstrates activity in a primary human T cell chemotaxis assay.

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

ASNFDCCLGY TDRILHPKFI VGFTRQLANE GCDINAIIFH TKKKLSVCAN PKQTWVKYIV RLLSKKVKNM

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.