Recombinant Human Myostatin Propeptide

Synonyms:

Growth Differentiation Factor 8, GDF8, GDF-8, MSLHP, MSTN

Species:

Human

Cat. No.:

CRM142C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$5,680.00 / Special Price: $3,720.00 BUY

Description:

Myostatin (GDF-8) is a member of the TGF-β superfamily and is a potent and specific negative regulator of skeletal muscle mass. The myostatin propeptide is known to bind and inhibit myostatin in vitro. This interaction is relevant in vivo, with a majority (>70%) of myostatin in serum bound to its propeptide acting as a negative regulator of myostatin. Propeptide consists of Asn24-Arg266.

Entrez Symbol:

MSTN

Uniprot ID:

O14793

Source:

E. coli

Molecular Weight:

27.8 kDa (244 aa)

Physical State:

Lyophilized

Formulation:

Sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

> 95.0%, determined by reducing and non-reducing SDS-PAGE

Endotoxin Level:

≤1 EUs/µg, by kinetic LAL

Amino Acid Sequence:

MNENSEQKEN VEKEGLCNAC TWRQNTKSSR IEAIKIQILS KLRLETAPNI SKDVIRQLLP KAPPLRELID QYDVQRDDSS DGSLEDDDYH ATTETIITMP TESDFLMQVD GKPKCCFFKF SSKIQYNKVV KAQLWIYLRP VETPTTVFVQ ILRLIKPMKD GTRYTGIRSL KLDMNPGTGI WQSIDVKTVL QNWLKQPESN LGIEIKALDE NGHDLAVTFP GPGEDGLNPF LEVKVTDTPK RSRR

Storage/Stability:

Store as supplied at -20°C to -80°C.