Recombinant Human PDGFR-beta, cytosolic region, GST-tag

Molecule:

PDGFRB

Synonyms:

Platelet-Derived Growth Factor Receptor beta, Beta-type platelet-derived growth factor receptor, Platelet-derived growth factor receptor 1, PDGFR-1, CD140b

Species:

Human

Cat. No.:

CRP037 pdf (datasheet)

Quantity/Size:

20 μg

Price:

$490.00 BUY

Description:

PDGFR-beta is a cell surface tyrosine kinase receptor for members of the plateletderived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The PDGF isoforms AA, BB, AB, CC, and DD are dimeric molecules. They bind two receptor molecules simultaneously and dimerize them upon binding. PDGFR-alpha binds the A, B, and C chains of PDGF with high affinity, whereas PDGFR-beta binds the B and D chain with high affinity.

Recombinant Human PDGFR-beta, cytosolic region, has a N-terminal GST tag to facilitate application in typical GST pull-down assays.

Entrez Symbol:

PDGFRB

Uniprot Name:

Platelet-derived growth factor receptor beta

Uniprot ID:

P09619

Data PDF:

CRP037

Source:

Sf9 insect cells

Formulation:

Liquid in 50 mM Tris-HCl, pH 8.0 + 100 mM NaCl + 1 mM DTT.

Purity:

> 90% by SDS-PAGE

Specific Activity:

3 units/µg (1 unit is defined as transfer of 1 pmol phosphate to the substrate peptide KKKSKDESVDYVPMLDMKG per minute at 30°C).

Storage/Stability:

Store at -80°C for up to 1 year. Upon initial thaw, prepare aliquots and store at -80°C. Avoid freeze / thaw cycles