JavaScript seem to be disabled in your browser.
You must have JavaScript enabled in your browser to utilize the functionality of this website.
Angiostatin is proteolytically processed from plasminogen, a secreted blood zymogen. Angiostatin reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth.
Recombinant Human Angiostatin, Kringle domains 1-3 (Ang K1-3) is a proteolytic fragment of Plasminogen (PLG) containing the first three of Angiostatin's four Kringle domains. Ang K1-3 is more active than Kringles 1-4. Recombinant Human Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids corresponding to residues 97-356.