Recombinant Human Pleiotrophin

Synonyms:

Heparin-binding brain mitogen, HBBM, Heparin-binding growth factor 8, Osteoblast-specifc factor 1, OSF-1

Species:

Human

Cat. No.:

CRH325C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,720.00 / Special Price: $2,100.00 BUY

Description:

Pleiotrophin (PTN) is a heparin-binding growth factor that has mitogenic effects on fibroblast, epithelial, and endothelial cells. PTN is made by many tissues, but is predominantly secreted by nervous tissue during development. PTN induces neurite outgrowth and is involved in tumor growth and metastasis. PTN binds with low affinity to the cell surface receptor nucleolin to inhibit HIV-1 infection. PNT also binds the receptor protein tyrosine phosphatase type Z (PTPRZ), syndecan-3, and anaplastic lymphoma kinase (ALK) receptors.

Uniprot ID:

P21246

Data PDF:

CRH325C

Source:

E. coli

Molecular Weight:

Monomer, 15.4 kDa (137 aa)

Physical State:

Lyophilized

Formulation:

Sterile-filtered solution containing 10 mM sodium phosphate, pH 7.5

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MGKKEKPEKK VKKSDCGEWQ WSVCVPTSGD CGLGTREGTR TGAECKQTMK TQRCKIPCNW KKQFGAECKY QFQAWGECDL NTALKTRTGS LKRALHNAEC QKTVTISKPC GKLTKPKPQA ESKKKKKEGK KQEKMLD

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.