Recombinant Human c-Raf 1 Kinase, Ras Binding Domain (aa 50-132)

Synonyms:

RAF proto-oncogene serine/threonine-protein kinase, cRaf, Raf-1

Species:

Human

Cat. No.:

CRR004 pdf (datasheet)

Quantity/Size:

50 μg

Price:

$490.00 BUY

Description:

Raf is a member of the serine/threonine proteine kinase family involved in regulation of cell growth and differentiation and is the most important effector of Ras. Full-length Raf is composed of three conserved regions responsible for interaction with Ras, for phosphorylation and for catalytic activity. Raf-RBD (Ras binding domain, amino acids 50 -132) mediates interaction with membrane-anchored Ras necessary for activation of the kinase activity of Raf.

Uniprot Name:

RAF proto-oncogene serine/threonine-protein kinase

Uniprot ID:

P04049

Data PDF:

CRR004

Source:

E. coli

Molecular Weight:

9.4 kDa (amino acids 50 - 132)

Formulation:

32 mM Tris-HCl, 200 mM NaCl, 5 mM MgCl2 , 5 mM DTT, pH 7.6

Purity:

> 95% by SDS-PAGE

Storage/Stability:

Store at -80°C for up to 1 year. Upon initial thaw, prepare aliquots and store at -80°C. Avoid freeze / thaw cycles