Recombinant Human SCGF-alpha

Synonyms:

CLEC11A, C-type lectin domain family 11 member A, SCGF-alpha, p47, C-type lectin superfamily member 3, Recombinant Human Stem Cell growth Factor-alpha

Species:

Human

Cat. No.:

CRS400B pdf (datasheet)

Quantity/Size:

10 μg

Price:

$520.00 BUY

Description:

Stem Cell Growth Factor-alpha (SCGF-alpha) is a newly discovered hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. Human SCGFalpha is a non-glycosilated species-specific cytokine that can support growth of primitive hematopoietic cells, and in combination of EPO or GM-CSF, it promotes proliferation of erythroid and myeloid progenitors, respectively.

Entrez Symbol:

CLEC11A

Uniprot ID:

Q9Y240

Data PDF:

CRS400B

Source:

E. coli

Molecular Weight:

33.9 kDa (305 aa)

Formulation:

Lyophilized from PBS.

Purity:

> 98% by SDS-PAGE gel and HPLC analyses.

Biological Activity:

ED50 ≤ 2.5 ng/ml, determined by the dose-dependent inhibition of human TF-1 cell proliferation, previously grown in media containing GM-CSF.

Endotoxin Level:

< 1 EU/µg

Amino Acid Sequence:

GHGARGAERE WEGGWGGAQE EEREREALML KHLQEALGLP AGRGDENPAG TVEGKEDWEM EEDQGEEEEE EATPTPSSGP SPSPTPEDIV TYILGRLAGL DAGLHQLHVR LHALDTRVVE LTQGLRQLRN AAGDTRDAVQ ALQEAQGRAE REHGRLEGCL KGLRLGHKCF LLSRDFEAQA AAQARCTARG GSLAQPADRQ QMEALTRYLR AALAPYNWPV WLGVHDRRAE GLYLFENGQR VSFFAWHRSP RPELGAQPSA SPHPLSPDQP NGGTLENCVA QASDDGSWWD HDCQRRLYYV CEFPF

Storage/Stability:

Stable for 1 year at -20°C to -80°C.