Recombinant Human SCGF-beta

Synonyms:

C-type lectin domain family 11 member A, SCGF-alpha, p47, C-type lectin superfamily member 3, Recombinant Human Stem Cell Growth Factor-beta, CLEC11A

Species:

Human

Cat. No.:

CRS401B pdf (datasheet)

Quantity/Size:

10 μg

Price:

$520.00 BUY

Description:

SCGF-α and -β are hematopoietic growth factor that exerts their activity at early stages of hematopoiesis. The SCGFs are non-glycosylated species-specific cytokines that can support growth of primitive hematopoietic cells, and in combination with EPO or GMCSF, promote proliferation or erthroid or myeloid progenitors, respectively.

Entrez Symbol:

CLEC11A

Uniprot Name:

C-type lectin domain family 11 member A

Uniprot ID:

Q9Y240

Data PDF:

CRS401

Source:

E. coli

Molecular Weight:

25.0 kDa (227 aa)

Formulation:

Lyophilized from PBS, pH 7.3

Purity:

> 98% by SDS-PAGE and HPLC analyses

Biological Activity:

ED50 typically 7 ng/ml, determined by its inhibitory effect on the proliferation of TF-1 cells, previously grown in media containing GM-CSF. For most in vitro applications, SCGF-ß exerts its biological activity in the concentration range of 0.2 to 20.0 ng/ml.

Endotoxin Level:

< 1 EU/µg

Amino Acid Sequence:

MGHGARGAER EWEGGWGGAQ EEEREREALM LKHLQEALGL PAGRGDENPA GTVEGKEDWE MEEDQGEEEE EEATPTPSSG PSPSPTPEDI VTYILGRLAG LDAGLHQLHV RLHALDTRVV ELTQGLRQLR NAAGDTRDAV QALQEAQGRA EREHGRLEGC LKGLRLGHKC FLLSRDFEAQ PSASPHPLSP DQPNGGTLEN CVAQASDDGS WWDHDCQRRL YYVCEFPF

Storage/Stability:

Stable for 1 year at -20°C to -80°C.