Recombinant Human Endomucin His-Tag, soluble

Synonyms:

EMCN, Endomucin-2, Mucin-14, MUC14, Gastric cancer antigen Ga34

Species:

Human

Cat. No.:

CS541 pdf (datasheet)

Quantity/Size:

20 μg

Price:

$850.00 BUY

Description:

Endomucin (endothelial sialomucin; also Endomucin-1/2 and Mucin-14) is an 80-120 kDa glycoprotein member of the Endomucin family of proteins. It is expressed on endothelial cells and depending upon its glycosylation pattern, can serve as either a pro- or antiadhesive molecule. Mouse Endomucin precursor is 261 amino acids in length. It is a type I transmembrane protein that contains a 170 aa extracellular domain (ECD) (aa21-190) and a 50 aa cytoplasmic region. Three splice variants exist in the ECD. One shows a deletion of aa91-141, a second shows a one aa substitution for aa91-129, and a third shows a one aa substitution for aa129-142. Over aa21-90, mouse Endomucin shares 60% and 30% aa identity with rat and human Endomucin, respectively.

Recombinant Human Soluble Endomucin corresponds to Asn18 to Ser190. A 6x His tag is fused to the N-terminal end of the sequence.

Entrez Symbol:

EMCN

Uniprot ID:

Q9ULC0

Data PDF:

CS541

Source:

E. coli

Molecular Weight:

20.4 kDa

Formulation:

Lyophilized from a solution of 10 mM sodium phosphate, pH 7.0.

Purity:

>95% by SDS-PAGE, visualized by silver stain

Amino Acid Sequence:

MGSSHHHHHH SSGLVPRGSH MGSHMNSTGV LEAANNSLVV TTTKPSITTP NTESLQKNVV TPTTGTTPKG TITNELLKMS LMSTATFLTS KDEGLKATTT DVRKNDSIIS NVTVTSVTLP NAVSTLQSSK PKTETQSSIK TTEIPGSVLQ PDASPSKTGT LTSIPVTIPE NTSQSQVIGT EGGKNASTSA TSRSYSS

Storage/Stability:

Stable for 1 year at -20°C to -80°C.