Recombinant Human TGF-beta 1

Molecule:

TGFbeta1

Synonyms:

Recombinant Human Transforming Growth Factor-beta 1, Precursor of Latency-asoociated protein (LAP), TGFB1, TGFbeta

Species:

Human

Cat. No.:

CS327C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$5,015.00 / Special Price: $3,880.00 BUY

Description:

Transforming Growth Factor-beta 1 (TGF-beta1) is a member of the TGF-beta superfamily. Members of this family are known to exhibit regulatory activity in immunity and proliferation pathways. TGF-beta1 signals through SMAD proteins via the TGF-beta1 RI and RII receptors. Mature human TGF-beta1 is a glycosylated homodimer.

Entrez Symbol:

TGFB1

Uniprot ID:

P01137

Data PDF:

CS327

Source:

CHO cells

Molecular Weight:

12.8/25.6 kDa (112/224 aa) dimer

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile buffer containing 0.1% trifluoroacetic acid (TFA) and trehalose in a 20:1 trehalose to protein ratio.

Purity:

≥ 95% by Reducing and Non-reducing SDS-PAGE

Biological Activity:

≤ 500 pg/ml, determined by the dose-dependent inhibition of IL-4-induced HT-2 cell proliferation.

Specific Activity:

≥ 2.0 x 10e6 U/mg Calibrated against recombinant human TGF-beta 1 Reference Standard NIBSC code: 89/514, rhTGF-beta1 = 2.2 x 10e4 RU/mg

Endotoxin Level:

≤ 1 EU/μg protein, determined by kinetic LAL

Amino Acid Sequence:

ALDTNYCFSS TEKNCCVRQL YIDFRKDLGW KWIHEPKGYH ANFCLGPCPY IWSLDTQYSK VLALYNQHNP GASAAPCCVP QALEPLPIVY YVGRKPKVEQ LSNMIVRSCK CS

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.