Recombinant Human TL1A

Synonyms:

Tumor necrosis factor ligand superfamily member 15, TNFSF15, TNF15, TNF ligandrelated molecule 1, Vascular endothelial cell growth inhibitor, , Human Recombinant TNF Ligand-related molecule 1, TL-1A, TL1A

Species:

Human

Cat. No.:

CRT005B pdf (datasheet)

Quantity/Size:

20 μg

Price:

$520.00 BUY

Description:

TL-1A belongs to the TNF superfamily of ligands. It is expressed predominantly in endothelial cells, and to a lesser extent in placenta, lung, kidney, skeletal muscle, pancreas, small intestine and colon. TL-1A inhibits endothelial cell proliferation and angiogenesis, and has been shown to induce NFkB activation, caspase activity, and apoptosis in responding cell lines. TL-1A interacts with TNFRSF25/DR3 receptor, but can also bind to a decoy receptor TNFRSF21/DR6.

Entrez Symbol:

TNFSF15

Uniprot ID:

O95150

Data PDF:

CRT005B

Source:

E. coli

Molecular Weight:

22 kDa (194 aa)

Formulation:

Lyophilized from PBS

Purity:

>98% by HPLC and SDS-PAGE

Biological Activity:

Determined by its ability to stimulate IFN-γ production by human PBMC using a concentration range of 10.0-100.0 ng/ml. Results will vary with PBMC donors.

Endotoxin Level:

<1 EU/µg

Amino Acid Sequence:

QLRAQGEASV QFQALKGQEF APSHQQVYAP LRADGDKPRA HLTVVRQTPT QHFKNQFPAL HWEHELGLAF TKNRMNYTNK FLLIPESGDY FIYSQVTFRG MTSECSEIRQ AGRPNKPDSI TVVITKVTDS YPEPTQLLMG TKSVCEVGSN WFQPIYLGAM FSLQEGDKLM VNVSDISLVD YTKEDKTFFG AFLL

Storage/Stability:

Stable for 1 year at -20°C to -80°C.