Recombinant Human TNFR1

Synonyms:

Recombinant Human TNF-RI/CD120a, Tumor necrosis factor receptor 1, TNFR1, Tumor necrosis factor receptor superfamily member 1A, CD120a

Species:

Human

Cat. No.:

CRT104C pdf (datasheet)

Quantity/Size:

1 mg

Price:

$2,720.00 / Special Price: $2,100.00 BUY

Description:

TNF Receptor I (TNFR1) is expressed in most tissues and is activated by soluble and membrane-bound TNF-α. TNFR1 is known to activate NF-κB and MAPK pathways and functions to induce inflammation, promote apoptotic cell death, inhibit tumorigenesis and inhibit viral replication

Entrez Symbol:

TNFRSF1A

Uniprot ID:

P19438

Data PDF:

CRT104

Source:

E. coli

Molecular Weight:

18.3 kDa, (162 aa)

Formulation:

Recombinant human TNFR1 is lyophilized from 10 mM sodium phosphate,, pH 7.5.

Purity:

≥ 95% by reducing and non-reducing SDS-PAGE

Biological Activity:

≤ 100 ng/ml, determined by neutralization of human TNFα induced L929 cell cytolysis.

Specific Activity:

≥ 1.0 x 10e4 units/mg

Endotoxin Level:

< 1EU/ug by kinetic LAL analysis

Amino Acid Sequence:

MDSVCPQGKY IHPQNNSICC TKCHKGTYLY NDCPGPGQDT DCRECESSGSF TASENHLRHC LSCSKCRKEM GQVEKSSCTV DRDTVCGCRK NQYRHYWSEN LFQCFNCSLC LNGTVHLSCQ EKQNTVCTCH AGFFLRENEC VSCSNCKKSL ECTKLCLPQI EN

Storage/Stability:

Lyophilized product is stable at room temperature for shipping purposes. After receipt, store at ≤20°C.