Recombinant Human VEGF-121 Animal Free

Synonyms:

VEGF-A, VPF, glioma-derived endothelial cell mitogen

Cat. No.:

CRH330C-AF pdf (datasheet)

Quantity/Size:

1 mg

Price:

$4,680.00 / Special Price: $3,080.00 BUY

Description:

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with one being VEGF-121. The VEGF-121 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell function.

Entrez Symbol:

VEGFA

Uniprot Name:

Vascular endothelial growth factor A

Uniprot ID:

P15692-9

Source:

E. coli

Molecular Weight:

Dimer, 14.1/28.3 kDa (121/242 aa)

Formulation:

Lyophilized from a sterile filtered solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 ≤ 5 ng/ml, determined by HUVEC proliferation.

Specific Activity:

≥2.0 x 105 U/mg

Endotoxin Level:

≤1 EU/µg by Kinetic LAL

Amino Acid Sequence:

MAPMAEGGGQ NHHEVVKFMD VYQRSYCHPI ETLVDIFQEY PDEIEYIFKP SCVPLMRCGG CCNDEGLECV PTEESNITMQ IMRIKPHQGQ HIGEMSFLQH NKCECRPKKD RARQENCDKP RR

Storage/Stability:

Upon receipt, store at -20°C to -80°C for up to 1 year.