Recombinant Human VEGFA (VEGF 165), Endotoxin Free

Molecule:

VEGFA

Synonyms:

MVCD1, VEGF165, VPF, vascular endothelial growth factor A, vascular permeability factor

Species:

Human

Cat. No.:

CRV122A pdf (datasheet)

Quantity/Size:

10 μg

Price:

$222.00 BUY

Description:

VEGFA, Vascular endothelial growth factor A, is the only growth factor that stimulates vascular permeability. It promotes endothelial proliferation and survival, angiogenesis, vasculognesis and inhibits apoptosis. VEGF mitogenic activity is specific for endothelial cell and that makes it distinct among other growth factors. VEGF is thought to be important in the pathophysiology of neuronal and other tumors, by functioning as a promter of angiogenesis for human gliomas. Human VEGF occurs in several molecular variants and the 165 form is the most common form in most tissues. Biological activities of VEGF are not species-specific and glycosylation is not required for biological activity.

Data PDF:

CRV122

Source:

Barley

Molecular Weight:

Recombinant human VEGFA contains 165 amino acids and a 16 aa His-tag for a total length of 181 aa and a predicted molecular mass of 21.3 kD.

Formulation:

Sterile filtered through a 0.2 ┬Ám filter. Lyophilized from PBS pH 7.2

Purity:

>95% by SDS-PAGE.

Biological Activity:

ED50 is < 20 ng/ml. Bioactivity was determined by the dose dependent effect of recombinant human VEGFA on proliferation of Human Umbilical Vein Endothelial Cells (HUVEC) cells

Specific Activity:

> 5.0 x 10E-4 U/mg