Recombinant Mouse C5a peptide, His-tag

Molecule:

Complement C5a

Synonyms:

C5a anaphylatoxin, hemolytic complement

Species:

Mouse

Cat. No.:

CRC238A pdf (datasheet)

Quantity/Size:

20 μg

Price:

$490.00 BUY

Description:

Mouse complement C5a anaphylatoxin is a 77-amino acid peptide generated during complement activation from the α-chain of complement C5. Mouse C5a shares 60% and 82% amino acid sequence identity to human and rat C5a, respectively. C5a binds to a signaling G-protein coupled receptor (GPCR) (C5aR/CD88), inducing neutrophil chemotaxis and endothelial cell activation. It also triggers an oxidative burst in macrophages and neutrophils, and induces degranulation, release of histamine in basophils and mast cells. The recombinant protein contains an N-terminal His-Tag sequence.

Entrez Symbol:

C5

Uniprot Name:

Complement C5

Uniprot ID:

P06684

Data PDF:

CRC238

Source:

E. coli

Molecular Weight:

9 kDa, (77 aa)

Physical State:

Lyophilized

Purity:

>95% by SDS-PAGE.

Biological Activity:

ED50 = 1-3 nM, based on enzyme release assay of myeloperoxidase.

Storage/Stability:

Store at -80°C