Recombinant Mouse CCL8 / MCP-2

Molecule:

CCL8

Synonyms:

C-C motif chemokine 8, Monocyte Chemotactic Protein 2, SCYA8

Species:

Mouse

Cat. No.:

CRM007A pdf (datasheet)

Quantity/Size:

5 μg

Price:

$85.00 BUY

Description:

Monocyte chemotactic protein 2 (MCP-2), also known as CCL8, is a cytokine that is important during allergic and inflammatory responses. MCP-2 activates mast cells, eosinophils, and basophils through the G protein-coupled chemokine receptors CCR1, CCR2B, and CCR5. MCP-2 and MCP-3 are two recently identified monocyte chemotactic proteins produced by human MG-63 osteosarcoma cells. Both MCP-2 and MCP-3 are members of the C-C family of chemokines and share 62% and 71% amino acid sequence identity, respectively, with MCP-1. MCP-3 also shares 58% amino acid identity with MCP-2.

Entrez Symbol:

Ccl8

Uniprot Name:

C-C motif chemokine 8

Uniprot ID:

Q9Z121

Data PDF:

CRM007

Source:

E. coli

Molecular Weight:

8.5 kDa (74 aa)

Physical State:

Lyophilized

Formulation:

Sterile-filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

≥ 95.0% by reducing and non-reducing SDS-PAGE

Endotoxin Level:

< 1EU/μg, as determined by kinetic LAL analysis.

Amino Acid Sequence:

GPDKAPVTCC FHVLKLKIPL RVLKSYERIN NIQCPMEAVV FQTKQGMSLC VDPTQKWVSE YMEILDQKSQ ILQP

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.