Recombinant Mouse CXCL2

Molecule:

CXCL2

Synonyms:

C-X-C motif chemokine 2, Macrophage inflammatory protein 2, MIP2

Species:

Mouse

Cat. No.:

CRC191C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,720.00 / Special Price: $2,220.00 BUY

Description:

Macrophage Inflammatory Protein-2 (MIP-2) was originally identified as a heparin binding protein secreted from a mouse macrophage cell line in response to endotoxin stimulation. Based on its protein and DNA sequences, MIP-2 is a member of the alpha (CXC) subfamily of chemokines. Similarly to other alpha chemokines, mouse MIP-2 is a potent chemotactic agent for leukocytes and hematopoietic cells. The expression of MIP-2 was found to be associated with neutrophil influx in pulmonary inflammation and glomerulonephritis, suggesting that MIP-2 may contribute to the pathogenesis of inflammatory diseases.

Uniprot Name:

C-X-C motif chemokine 2

Uniprot ID:

P10889

Data PDF:

CRC191

Source:

E. coli

Molecular Weight:

7.9 kDa (73 aa) monomer

Formulation:

Lyophilized from sterile filtered 10 mM sodium phosphate, pH 7.5

Purity:

≥ 95% by reducing and non-reducing SDS-PAGE analysis

Endotoxin Level:

≤ 1 EU/μg as determined by kinetic LAL analysis

Amino Acid Sequence:

AVVASELRCQ CLKTLPRVDF KNIQSLSVTP PGPHCAQTEV IATLKGGQKV CLDPEAPLVQ KIIQKILNKG KAN

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/mL and gently pipette the solution up and down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution.

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year. Upon reconstitution, prepare working aliquots and store at -20°C to -80°C. It is recommended that a carrier protein such as 0.1% HSA or BSA is added for long term storage. Avoid repeated freeze-thaw cycles.