Recombinant Mouse Exodus-2/CCL21

Molecule:

CCL21

Synonyms:

C-C motif chemokine 21a, 6Ckine, Beta-chemokine exodus-2, Small-inducible cytokine A21a, Thymus-derived chemotactic agent 4, TCA4

Species:

Mouse

Cat. No.:

CRE401B pdf (datasheet)

Quantity/Size:

20 μg

Price:

$185.00 BUY

Description:

Exodus-2, also known as CCL2, is a chemokine that is strongly produced in the human lymph nodes and spleen. Exodus-2 signals through the chemokine receptor CCR7 to regulate thymocyte and activated T cell migration. Exodus-2 also mediates the homing of lymphocytes to the lymphatic system. Human and mouse Exodus-2 proteins share greater than 85% amino acid sequence identity.

Entrez Symbol:

Ccl21a

Uniprot Name:

C-C motif chemokine 21a

Uniprot ID:

P84444

Data PDF:

CRE401

Source:

E. coli

Molecular Weight:

12.1 kDa (110 aa) monomer

Formulation:

Lyophilized from a sterile-filtered solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

≥ 95% by reducing and non-reducing SDS-pAGE

Biological Activity:

Fully biologically active when compared to the standard. Determined by its ability to chemoattract total mouse T cell population using a concentration range of 10.0 -100.0 ng/ml.

Endotoxin Level:

Less than 1 EU/μg of recombinant mouse Exodus-2/CCL21 as determined by LAL method.

Amino Acid Sequence:

SDGGGQDCCL KYSQKKIPYS IVRGYRKQEP SLGCPIPAIL FLPRKHSKPE LCANPEEGWV QNLMRRLDQP PAPGKQSPGC RKNRGTSKSG KKGKGSKGCK RTEQTQPSRG

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to a concentration of 0.1 mg/mL and gently pipet the solution up and down the sides of the vial. DO NOT VORTEX. Allow several minutes for reconstitution.

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year. Upon reconstitution, prepare working aliquots and store at -20°C to -80°C. It is recommended that a carrier protein such as 0.1% HSA or BSA is added for long term storage. Avoid repeated freeze-thaw cycles.