Recombinant Mouse FGF-basic

Synonyms:

FGF2, HBGF-2, Prostatropin

Species:

Mouse

Cat. No.:

CRM425C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$1,220.00 / Special Price: $940.00 BUY

Description:

Basic fibroblast growth factor (FGF-basic), also known as FGF-2, is expressed by endothelial cells and is a mediator of angiogenesis. FGF-basic also has cardioprotective functions during heart injury. Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro.

Entrez Symbol:

Fgf2

Uniprot Name:

Fibroblast growth factor 2

Uniprot ID:

P15655

Source:

E. coli

Molecular Weight:

Monomer, 16.5 kDa (146 aa)

Physical State:

Lyophilized

Formulation:

Sterile-filtered solution containing 10 mM sodium phosphate, 50 mM sodium chloride, pH 7.5

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 ≤ 2.5 ng/ml, determined by the dose-dependent proliferation 3T3 cells.

Specific Activity:

≥ 4.0 x 10e6 units/mg

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MPALPEDGGA AFPPGHFKDP KRLYCKNGGF FLRIHPDGRV DGVREKSDPH VKLQLQAEER GVVSIKGVCA NRYLAMKEDG RLLASKCVTE ECFFFERLES NNYNTYRSRK YSSWYVALKR TGQYKLGSKT GPGQKAILFL PMSAKS

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.