Recombinant Mouse FLT3 Ligand

Molecule:

FLT3LG

Synonyms:

FLt3 L, Fms-related tyrosine kinase 3 ligand

Species:

Mouse

Cat. No.:

CRF115B pdf (datasheet)

Quantity/Size:

10 μg

Price:

$235.00 BUY

Description:

FMS-related Tyrosine Kinase 3 Ligand (FLT-3 Ligand) is a growth factor important for the proliferation of hematopoietic cells. FLT-3 Ligand binds to, and transmits signals through, the receptor tyrosine kinase known as FMS-like Tyrosine Kinase-3 (FLT-3). FLT-3 Ligand promotes long-term expansion and differentiation of human pro-B cells in the presence of IL-7 or in combination of IL-7 and IL-3. Human FLT-3 Ligand can stimulate the proliferation of cells expressing murine FLT-3 receptors. Recombinant mouse FLT-3 Ligand is a non-glycosylated protein, containing 144 amino acids, with a molecular weight of 16.4 kDa.

Entrez Symbol:

Flt3l

Uniprot Name:

SL cytokine

Uniprot ID:

P49772

Data PDF:

CRF115

Source:

E. coli

Molecular Weight:

16.4 kDa

Physical State:

Sterile filtered white lyophilized (freeze-dried) powder.

Formulation:

Recombinant mouse FLT3-Ligand is lyophilized with no additives

Purity:

>98% by SDS-PAGE gel and RP-HPLC

Biological Activity:

The activity is determined by the dose-dependent proliferation of mouse AML5 cells and s typically 5-8 ng/mL.

Endotoxin Level:

<0.1 ng/�g

Amino Acid Sequence:

MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ

Storage/Stability:

Store at -20°C