Recombinant Mouse FLT3 Ligand

Molecule:

FLT3L

Synonyms:

FLt3 L, Fms-related tyrosine kinase 3 ligand

Species:

Mouse

Cat. No.:

CRF115C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$3,620.00 / Special Price: $2,800.00 BUY

Description:

FMS-related Tyrosine Kinase 3 Ligand (FLT-3 Ligand) is a growth factor important for the proliferation of hematopoietic cells. FLT-3 Ligand binds to, and transmits signals through, the receptor tyrosine kinase known as FMS-like Tyrosine Kinase-3 (FLT-3). FLT-3 Ligand promotes long-term expansion and differentiation of human pro-B cells in the presence of IL-7 or in combination of IL-7 and IL-3. Human FLT-3 Ligand can stimulate the proliferation of cells expressing murine FLT-3 receptors.

Entrez Symbol:

Flt3l

Uniprot Name:

Fms-related tyrosine kinase 3 ligand

Uniprot ID:

P49772

Source:

E. coli

Molecular Weight:

Monomer, 18.6 kDa (163 aa)

Physical State:

Lyophilized

Formulation:

Recombinant mouse FLT3-Ligand is lyophilized with no additives

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

≤10 ng/ml, determined by the dose-dependent proliferation of mouse OCI-AML5 cells

Specific Activity:

≥ 1.0 x 10e5 units/mg

Endotoxin Level:

≤1 EU/μg by kinetic LAL analysis

Amino Acid Sequence:

MTPDCYFSHS PISSNFKVKF RELTDHLLKD YPVTVAVNLQ DEKHCKALWS LFLAQRWIEQ LKTVAGSKMQ TLLEDVNTEI HFVTSCTFQP LPECLRFVQT NISHLLKDTC TQLLALKPCI GKACQNFSRC LEVQCQPDSS TLLPPRSPIA LEATELPEPR PRQ

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.