Recombinant Mouse Follistatin

Synonyms:

Recombinant Mouse Follistatin, FST, FS, Activin-binding protein.

Species:

Mouse

Cat. No.:

CS304C pdf (datasheet)

Quantity/Size:

1 mg

Price:

$4,820.00 / Special Price: $3,720.00 BUY

Description:

Follistatin is an autocrine acting protein that is expressed by many tissues, but at noteably higher levels in the ovary and skin. Follistatin functions to negatively regulate the signaling of a wide variety of TGF-beta family members (activin, BMPs, myostatin, GDF-11 and TGF-beta 1). Mechanistically, follistatin works as an antagonist by complexing with TGF-beta family members to prevent them from interacting with their signaling receptors.

Entrez Symbol:

Fst

Uniprot ID:

P47931

Data PDF:

CS304

Source:

E. coli

Molecular Weight:

31.6 kDa (289 aa) monomer

Formulation:

Lyophilized from a sterile filtered solution of 10 mM sodium phosphate, 50 mM NaCl, pH 7.5

Purity:

≥ 90% as determined by reducing and nonreducing SDS-PAGE

Biological Activity:

Typical ED50 < 1mg/ml, by dose-dependent MCP-11 cell proliferation.

Endotoxin Level:

≤ 5 EU/μg by kinetic LAL analysis

Amino Acid Sequence:

MGNCWLRQAK NGRCQVLYKT ELSKEECCST GRLSTSWTEE DVNDNTLFKW MIFNGGAPNC IPCKETCENV DCGPGKKCRM NKKNKPRCVC APDCSNITWK GPVCGLDGKT YRNECALLKA RCKEQPELEV QYQGKCKKTC RDVFCPGSST CVVDQTNNAY CVTCNRICPE PSSSEQYLCG NDGVTYSSAC HLRKATCLLG RSIGLAYEGK CIKAKSCEDI QCGGGKKCLW DSKVGRGRCS LCDELCPDSK SDEPVCASDN ATYASECAMK EAACSSGVLL EVKHSGSCN

Storage/Stability:

Store lyophilized protein at -20°C to -80°C.