Recombinant Mouse G-CSF/CSF3

Molecule:

G-CSF/CSF3

Synonyms:

Colony Stimulating Factor 3, CSF3, CSF-beta, DF, G-CSF

Species:

Mouse

Cat. No.:

CRG301C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$4,140.00 / Special Price: $2,720.00 BUY

Description:

Granulocyte Colony-Stimulating Factor, or G-CSF, is a growth factor that is considered the most potent inducer of terminal differentiation to granulocytes and macrophages of leukemic myeloid cell lines. The synthesis of G-CSF can be induced by bacterial endotoxins, TNF, IL-1 and GM-CSF. Prostaglandin E2 inhibits the synthesis of G-CSF, while in epithelial, endothelial, and fibroblastic cells secretion of G-CSF is induced by IL-17. Human and mouse G-CSF are cross-reactive.

Entrez Symbol:

Csf3

Uniprot Name:

Granulocyte colony-stimulating factor

Uniprot ID:

P09920

Data PDF:

CRG301

Source:

E. coli

Molecular Weight:

Monomer, 19.1 kDa (179 aa)

Physical State:

Lyophilized

Formulation:

Sterile filtered aqueous solution containing 10 mM sodium citrate, pH 3.0

Purity:

≥ 95%, by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 ≤50 pg/ml, determined by the dose-dependent proliferation of mouse NFS-60 cells.

Specific Activity:

≥ 2.0 x 10e7 units/mg

Endotoxin Level:

≤ 1 EU/μg, by kinetic LAL analysis

Amino Acid Sequence:

MVPLVTVSAL PPSLPLPRSF LLKSLEQVRK IQASGSVLLE QLCATYKLCH PEELVLLGHS LGIPKASLSG CSSQALQQTQ CLSQLHSGLC LYQGLLQALS GISPALAPTL DLLQLDVANF ATTIWQQMEN LGVAPTVQPT QSAMPAFTSA FQRRAGGVLA ISYLQGFLET ARLALHHLA

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.