Recombinant Mouse GRO-alpha (CXCL1)

Molecule:

CXCL1

Synonyms:

C-X-C motif chemokine 1, CXCL1, Secretory protein N51, Platelet-derived growth factor-inducible protein KC

Species:

Mouse

Cat. No.:

CRM426C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,720.00 / Special Price: $2,220.00 BUY

Description:

Growth regulated alpha protein (GRO-α), also known as CXCL1, is a chemokine that has mitogenic properties and is a neutrophil chemoattractant. GRO- α is secreted by macrophages, epithelial cells, neutrophils, and melanomas. GRO- α signals through the CXCR2 chemokine receptor and is important during spinal cord formation, inflammation, angiogenesis, tumorigenesis, and wound healing.

Entrez Symbol:

Cxcl1

Uniprot Name:

Growth-regulated alpha protein

Uniprot ID:

P12850

Source:

E. coli

Molecular Weight:

Monomer, 7.8 kDa (72 aa)

Formulation:

Lyophilized from a sterile-filtered solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

This product demonstrates human neutrophil chemotaxis at a lower limit of 10 ng/ml.

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

APIANELRCQ CLQTMAGIHL KNIQSLKVLP SGPHCTQTEV IATLKNGREA CLDPEAPLVQ KIVQKMLKGV PK

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water to reconstitute to a recommended concentration of 0.1 mg/mL and gently pipet solution up and down sides of vial. DO NOT VORTEX. Allow several minutes for reconstitution. A small amount of precipitate may be seen.

Storage/Stability:

Upon receipt, store as supplied at -20o C to -80o C for up to one year. Upon reconstitution, the preparation is stable for up to one month at 2-8o C. For long term storage, reconstitute in working aliquots in 0.1% BSA solution and store at -80o C. Avoid repeated freeze-thaw cycles.