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Interferon-beta has antiviral, antibacterial and anticancer activities. Influenza A viruses not only inhibit IFN-beta gene induction but also supress Type-I IFN signaling via a mechanism involving induction of the SOCS-3 protein. Intracellular bacteria and cytosolic poly (dA-dT) trigger IFN-beta responses in different human cells without requiring human ZBP1.
Recombinant Mouse Interferon beta is a single, non-glycosylated polypeptide chain containing 182 amino acids (22-182 a.a.) that is fused to a 21 amino acid His tag at the N-terminus.