Synonyms:
IL-16, Lymphocyte Chemoattractant Factor, LCF
Description:
Interleukin 16 (IL-16) is produced primarily by CD4+ and CD8+ T-cells and acts as a chemo-attractant for lymphocytes, monocytes, eosinophils, dendritic cells and Langerhans cells. Additionally, IL-16 has been reported to upregulate IL-2 receptor (CD25), induce progression of cells to the GI phase and suppress HIV & SIV replication.
Molecular Weight:
13.2 kDa (127 aa)
Physical State:
Lyophilized
Formulation:
Sterile filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5
Purity:
> 95 % by reducing and non-reducing SDS-PAGE
Biological Activity:
This product demonstrates primary human T cell chemotaxis, detectable at 5 ng/ml.
Endotoxin Level:
≤ 1 EU/µg, by kinetic LAL
Amino Acid Sequence:
MHDLNSSTDS AASASAASDI SVESKEATVC TVTLEKTSAG LGFSLEGGKG SLHGDKPLTI NRIFKGDRTG EMVQPGDEIL QLAGTAVQGL TRFEAWNVIK ALPDGPVTIV IRRTSLQCKQ TTASADS
Storage/Stability:
Store as supplied at -20°C to -80°C for up to 1 year.
