Recombinant Mouse IL-31

Molecule:

IL-31

Synonyms:

Interleukin 31

Species:

Mouse

Cat. No.:

CRI228C pdf (datasheet)

Quantity/Size:

1 mg

Price:

$4,820.00 / Special Price: $3,720.00 BUY

Description:

Interleukin-31 (IL-31) is an immunoregulatory cytokine that is mainly expressed by activated TH2 cells. IL-31 signals through the IL-31 Receptor (IL-31RA) and the oncostain receptor (OSMR), which are expressed on monocytes, epithelial cells, and keratinocytes. IL-31 promotes allergic reactions and inflammatory skin diseases.

Entrez Symbol:

Il31

Uniprot ID:

Q6EAL8

Source:

E. coli

Molecular Weight:

15.7 kDa (141 aa)

Physical State:

Lyophilized

Formulation:

Sterile (0.2 micron) filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5

Purity:

≥ 95%, by reducing and non-reducing SDS-PAGE.

Biological Activity:

This product demonstrates dose dependent production of IL-8 from human PBMCs, detected by ELISA. Typical ED50 < 25 ng/mL.

Endotoxin Level:

≤ 1 EU/μg, by kinetic LAL.

Amino Acid Sequence:

MTCSLSFGAP ISKEDLRTTI DLLKQESQDL YNNYSIKQAS GMSADESIQL PCFSLDREAL TNISVIIAHL EKVKVLSENT VDTSWVIRWL TNISCFNPLN LNISVPGNTD ESYDCKVFVL TVLKQFSNCM AELQAKDNTT C

Storage/Stability:

Store as supplied at -20°C to -80°C.