Recombinant Mouse IL-33, Animal Free

Molecule:

IL-33

Synonyms:

IL-33, NP-HEV, IL-1F11, DVS27-related protein, interleukin-1 family member 11, nuclear

Species:

Mouse

Cat. No.:

CSI20129C-AF pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$6,260.00 / Special Price: $4,100.00 BUY

Description:

Recombinant Mouse IL-33 contains 159 amino acid residues. Background: Interleukin-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through the IL -1RL1/ST2 receptor activating NF-kappaB and MAP kinases. IL-33 induces production of TH2 cell related cytokines, including IL-4, IL-5 and IL-13, and exerts multiple inflammation related bioactivities.

Entrez Symbol:

Il33

Uniprot Name:

Interleukin-33

Uniprot ID:

Q8BVZ5

Data PDF:

CSI20129AF

Source:

E. coli

Molecular Weight:

Approximately 17.7 kDa protein containing 159 amino acid residues.

Physical State:

Lyophilized

Formulation:

Lyophilized from a 0.2 μm filtered solution of 10 mM sodium phosphate, pH 7.5.

Purity:

≥ 90% by Reducing and Non-Reducing SDS-PAGE

Biological Activity:

ED50 ≤ 2 ng/ml, determined by a cell proliferation assay using murine D10S cells

Specific Activity:

≥ 5 x 10e5 units/mg

Endotoxin Level:

≤ 1EU/μg of rmIL-33 as determined by Kinetic LAL

Amino Acid Sequence:

MSIQGTSLLTQ SPASLSTYND QSVSFVLENG CYVINVDDSG KDQEQDQVLL RYYESPCPAS QSGDGVDGKK LMVNMSPIKD TDIWLHANDK DYSVELQRGD VSPPEQAFFV LHKKSSDFVS FECKNLPGTY IGVKDNQLAL VEEKDESCNN IMFKLSKI

Reconstitution:

Centrifuge vial prior to opening. Add sterile distilled water or aqueous buffer to a concentration of 0.1-1.0 mg/mL. Further dilutions should be made in appropriate buffered solutions.

Storage/Stability:

Store at -20°C to -80°C for 1 year