Recombinant Mouse IP-10 / CXCL10

Molecule:

CXCL10

Synonyms:

10 kDa Interferon gamma-induced protein, C-X-C motif chemokine 10, Gamma-IP10, IP-10, C7, small-inducible cytokine B10, CXCL10, CRG-2

Species:

Mouse

Cat. No.:

CRM429C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,720.00 / Special Price: $2,100.00 BUY

Description:

Interferon gamma-induced protein 10 (IP-10), or CXCL10, is a chemokine secreted by monocytes, endothelial cells and fibroblasts in response to interferon gamma (IFNγ). IP-10 functions as a chemoattractant for activated T cells, monocytes, dendritic, and natural killer (NK) cells that express the G protein-coupled receptor CXCR3. IP-10 is an important factor in autoimmune diseases such as Hashimoto's thyroiditis, Graves' disease, and Type 1 diabetes mellitus.

Entrez Symbol:

Cxcl10

Uniprot Name:

C-X-C motif chemokine 10

Uniprot ID:

P17515

Source:

E. coli

Molecular Weight:

Monomer, 8.7 kDa (77 aa)

Physical State:

Lyophilized

Formulation:

Sterile-filtered solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Demonstrates primary human T cell chemotaxis at a lower limit of 5 ng/ml.

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

IPLARTVRCN CIHIDDGPVR MRAIGKLEII PASLSCPRVE IIATMKKNDE QRCLNPESKT IKNLMKAFSQ KRSKRAP

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.