Recombinant Mouse M-CSF

Molecule:

M-CSF

Synonyms:

Macrophage Colony Stimulating Factor, CSF-1

Species:

Mouse

Cat. No.:

CRM008C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$4,620.00 / Special Price: $3,020.00 BUY

Description:

Macrophage Colony Stimulating Factor (M-CSF) is a hematopoietic cytokine/ growth factor produced by a wide variety of cells. M-CSF controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. M-CSF acts through the CSF receptor 1.

Entrez Symbol:

Csf1

Uniprot ID:

P07141

Source:

E. coli

Molecular Weight:

Dimer, 18.2/36.4 kDa (156/312 aa)

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile-filtered aqueous solution containing 10mM sodium phosphate, 50 mM sodium chloride, pH 7.5.

Purity:

> 95% by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 < 10 ng/ml, determined by dose-dependent proliferation of M-NFS-60 cells.

Specific Activity:

≥ 1.0 x 10e5 U/mg

Endotoxin Level:

< 1 EU/µg of protein by kinetic LAL

Amino Acid Sequence:

MKEVSEHCSH MIGNGHLKVL QQLIDSQMET SCQIAFEFVD QEQLDDPVCY LKKAFFLVQD IIDETMRFKD NTPNANATER LQELSNNLNS CFTKDYEEQN KACVRTFHET PLQLLEKIKN FFNETKNLLE KDWNIFTKNC NNSFAKCSSR DVVTKP

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.