Recombinant Mouse MIF

Molecule:

MIF

Synonyms:

Macrophage migration inhibitory factor, delayed early response protein 6, DER6, glycosylation inhibiting factor, GIF, L-dopamine isomerase.

Species:

Mouse

Cat. No.:

CRM433C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$3,200.00 / Special Price: $2,100.00 BUY

Description:

Macrophage migration inhibitory factor (MIF) is a pro-inflammatory lymphokine that functions during cell-mediated immmunity. MIF promotes fibroblast migration by inducing interleukin 1 (IL-1), interleukin 8 (IL-8), and matrix metalloproteinase (MMP) expression. In interferon-gamma-activated macrophages, MIF stimulates nitric oxide (NO) production and tumor necrosis factor alpha (TNF-α) secretion.

Entrez Symbol:

Mif

Uniprot Name:

Macrophage migration inhibitory factor

Uniprot ID:

P34884

Source:

E. coli

Molecular Weight:

Monomer, 12.5 kDa (115 aa)

Physical State:

Lyophilized

Formulation:

Sterile-filtered solution containing 10 mM sodium phosphate, pH 7.5

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Activity determined by ERK pathway activation in RAW cells, detected via Western Blot

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MPMFIVNTNV PRASVPEGFL SELTQQLAQA TGKPAQYIAV HVVPDQLMTF SGTNDPCALC SLHSIGKIGG AQNRNYSKLL CGLLSDRLHI SPDRVYINYY DMNAANVGWN GSTFA

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.