Recombinant Mouse MIP-1 beta / CCL4

Molecule:

CCL4

Synonyms:

C-C motif chemokine, CCL4, ACT-2

Species:

Mouse

Cat. No.:

CRM430C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,720.00 / Special Price: $2,100.00 BUY

Description:

Macrophage inflammatory protein-1 beta (MIP-1 β), also known as CCL4, is produced by macrophages and functions as a mitogen-inducible cytokine. MIP-1 β signals through the chemokine receptor CCR5 to chemoattract immune cells. MIP-1 β induces inflammatory responses, including neutrophil superoxide production. The MIP-1 β and MIP-1 α heterodimer exhibits antiviral activity against the human immunodeficiency virus 1 (HIV-1).

Entrez Symbol:

Ccl4

Uniprot Name:

C-C motif chemokine

Uniprot ID:

Q5QNV9

Source:

E. coli

Molecular Weight:

Monomer, 7.8 kDa (69 aa)

Physical State:

Lyophilized

Formulation:

Sterile-filtered solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Activity determined by THP-1 chemotaxis assay, acceptance ≤ 100 ng/mL

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

APMGSDPPTS CCFSYTSRQL HRSFVMDYYE TSSLCSKPAV VFLTKRGRQI CANPSEPWVT EYMSDLELN

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.