Recombinant Mouse MIP-3 alpha / CCL20

Molecule:

CCL20

Synonyms:

C-C motif chemokine 20, CCL20, macrophage inflammatory protein 3 alpha, small-inducible cytokine A20, CC chemokine LARC, CC chemokine ST38, beta-chemokine exodus-1

Species:

Mouse

Cat. No.:

CRM431C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$2,720.00 / Special Price: $2,100.00 BUY

Description:

Macrophage inflammatory protein-3 alpha (MIP-3 α), also called CCL20, is expressed in the liver, lungs, lymph nodes, and peripheral blood lymphocytes. MIP-3 α expression is strongly induced by inflammatory signals, and downregulated by the anti-inflammatory cytokine interleukin 10 (IL-10). MIP-3 α signals through the G protein-coupled receptor CCR6 to function as a chemoattractant to lymphocytes and dendritic cells.

Entrez Symbol:

Ccl20

Uniprot Name:

C-C motif chemokine 20

Uniprot ID:

O89093

Source:

E. coli

Molecular Weight:

Monomer, 8 kDa (70 aa)

Physical State:

Lyophilized

Formulation:

Sterile-filtered solution containing 0.1% Trifluoroacetic Acid (TFA)

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Demonstrates primary human T cell chemotaxis at a lower limit of 5 ng/mL.

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

ASNYDCCLSY IQTPLPSRAI VGFTRQMADE ACDINAIIFH TKKRKSVCAD PKQNWVKRAV NLLSLRVKKM

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.