Recombinant Mouse NGF beta Animal Free

Molecule:

NGF beta

Synonyms:

Ngfb, beta-NGF

Species:

Mouse

Cat. No.:

CRN006C-AF pdf (datasheet)

Quantity/Size:

1 mg

Price:

$2,990.00 / Special Price: $2,300.00 BUY

Description:

Nerve Growth Factor (NGF-beta) is a neurotrophic factor related to BDNF, NT-3 and NT-4 and is involved in the development and maintenance of the sensory and sympathetic nervous systems. β-NGF signals through the low affinity nerve growth factor receptor (LNGFR) and the tropomyosin receptor kinase A (TrkA) to activate PI3K, Ras, and PLC signaling pathways. β-NGF is also involved in the growth, differentiation, and survival of B lymphocytes. Human, mouse, and rat β-NGF proteins are cross-reactive. 

Manufactured without Animal-derived products, in an Animal Free facility.

Entrez Symbol:

Ngf

Uniprot Name:

Beta-nerve growth factor

Uniprot ID:

P01139

Data PDF:

CRN006-AF

Source:

E. coli

Molecular Weight:

13.6 kDa/27.2 kDa (121/242 amino acids) noncovalent homodimer

Physical State:

Lyophilized

Formulation:

Sterile filtered aqueous solution containing 0.1% TFA

Purity:

≥95% determined by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 < 5 ng/ml, determined by dose-dependent proliferation of TF-1 cells.

Specific Activity:

> 2.0 x 10e5 Units/mg

Endotoxin Level:

≤ 1 EU/μg by kinetic LAL analysis.

Amino Acid Sequence:

MSSTHPVFHM GEFSVCDSVS VWVGDKTTAT DIKGKEVTVL AEVNINNSVF RQYFFETKCR ASNPVESGCR GIDSKHWNSY CTTTHTFVKA LTTDEKQAAW RFIRIDTACV CVLSRKATRR G

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.