Recombinant Mouse Thrombopoietin Animal Free

Synonyms:

Megakaryocyte Colony Stimulating Factor, c-MPL Ligand, MGDF

Species:

Mouse

Cat. No.:

CRT401C-AF pdf (datasheet)

Quantity/Size:

1 mg

Price:

$5,220.00 / Special Price: $3,420.00 BUY

Description:

Thrombopoietin (TPO) is a growth factor that is produced by the liver and kidney. TPO acts through the TPO receptor to promote megakaryocyte maturation and differentiation, which leads to the production of platelets. Recombinant mouse TPO is a non-glycosylated protein, containing 174 amino acids (which comprise the receptor binding domain).

Entrez Symbol:

Thpo

Uniprot ID:

P40226

Data PDF:

CRT401-AF

Molecular Weight:

18.7 kDa

Physical State:

Lyophilized

Formulation:

Sterile filtered aqueous solution containing 10 mM sodium phosphate, pH 7.5

Purity:

≥95% as determined by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 < 1 ng/ml, determined by the dose-dependent stimulation of MO7e cells.

Specific Activity:

> 2.0 x 105 units/ml

Endotoxin Level:

≤1EU/μg protein as measured by kinetic LAL analysis. Manufactured without Animal-derived products, in an Animal Free facility.

Amino Acid Sequence:

SPVAPACDPR LLNKLLRDSH LLHSRLSQCP DVDPLSIPVL LPAVDFSLGE WKTQTEQSKA QDILGAVSLL LEGVMAARGQ LEPSCLSSLL GQLSGQVRLL LGALQGLLGT QLPLQGRTTA HKDPNALFLS LQQLLRGKVR FLLLVEGPTL CVRRTLPTTA VPSSTSQLLT LNKF

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.