Recombinant Mouse VEGF-165

Molecule:

VEGFA

Synonyms:

Vascular endothelial growth factor A, VEGF-A, VPF, glioma-derived endothelial cell mitogen

Species:

Mouse

Cat. No.:

CRM434C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$4,260.00 / Special Price: $2,800.00 BUY

Description:

Vascular endothelial growth factor A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxide-dependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

Entrez Symbol:

Vegfa

Uniprot Name:

Vascular endothelial growth factor A

Uniprot ID:

Q00731-2

Source:

E. coli

Molecular Weight:

Dimer, 19.4/38.8 kDa (165/230 aa)

Physical State:

Lyophilized

Formulation:

Sterile-filtered solution containing 0.1% Trifluoroacetic (TFA)

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Activity is determined by the dose-dependent proliferation of human umbilical vein endothelial cells (HUVEC) and typical ED50 is < 5 ng/mL.

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

Dimer, 19.4/38.8 kDa (165/230 aa)

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.