Recombinant Rat GDNF Animal Free

Molecule:

GDNF

Synonyms:

Recombinant Rat GDNF, Astrocyte-derived trophic factor, ATF-1

Species:

Rat

Cat. No.:

CRR305C-AF pdf (datasheet)

Quantity/Size:

1 mg

Price:

$5,300.00 / Special Price: $4,100.00 BUY

Description:

Glial cell-derived neurotrophic factor (GDNF) is a neurotrophic factor that signals through a multicomponent receptor system to activate receptor tyrosine kinase RET signaling. GDNF promotes dopamine uptake, prevents motor neuron apoptosis, and supports the survival and differentiation of neurons.

Manufactured without Animal-derived products, in an Animal Free facility.

Entrez Symbol:

Gdnf

Uniprot ID:

Q07731

Data PDF:

CRR305-AF

Source:

E. coli

Molecular Weight:

Dimer, 15.1/30.1 kDa (135/270 aa)

Formulation:

Lyophilized from a sterile-filtered solution containing 10mM sodium phosphate, pH 7.5

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Typical ED50 < 0.1 µg/m, determined by dose-dependent proliferation of C6 cells.

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MSPDKQAAAL PRRERNRQAA AASPENSRGK GRRGQRGKNR GCVLTAIHLN VTDLGLGYET KEELIFRYCS GSCEAAETMY DKILKNLSRS RRLTSDKVGQ ACCRPVAFDD DLSFLDDSLV YHILRKHSAK RCGCI

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.