Recombinant Rat IGFBP4

Cat. No.:

BP4CU015 pdf (datasheet)

Quantity/Size:

15 μg

Price:

$290.00 BUY

Description:

Rat Insulin-like growth factor binding protein-4 is a 233 amino acid protein which is a member of a family of six circulating proteins that bind IGF-I and IGF-II with high affinity and modulate their metabolic and mitogenic effects. Rat IGFBP-4 is present in biological fluids as an N-linked glycosylated form. IGFBP-4 is primarily an inhibitor of IGF action and does not generally bind to cell surfaces.

This product has an N-terminal glycine and is non-glycosylated. [Gly1]IGFBP-4 has the same binding characteristics to IGF-I as glycosylated IGFBP-4.

Entrez Symbol:

Igfbp4

Uniprot Name:

Insulin-like Growth Factor Binding Protein-4

Uniprot ID:

P21744

Data PDF:

BP4CU015

Source:

E. coli

Molecular Weight:

Non-glycosylated rat IGFBP-4 is 25.7 kDa

Physical State:

Lyophilized

Formulation:

10 mM HCl

Purity:

> 95% by HPLC and SDS-PAGE

Biological Activity:

Binding of IGF-I: IC50 = 0.24 nM

Endotoxin Level:

< 0.1 EU/µg

Reconstitution:

See Protocol 1100, Handling of IGF Binding Proteins 1-6

Storage/Stability:

Store at 2-8°C.