Synonyms:
Recombinant Rat Interleukin-17F, IL-17F
Description:
Interleukin 17F (IL-17F) is one of six members of the IL-17 family (IL-17A-F) secreted by
activated CD4+ T cells and monocytes. Similar to IL-17A, IL-17F binds to the IL17 RC
receptor and promotes the production of IL-6, IL-8, G-CSF and increases matrix turnover
rates. IL-17F is also thought to inhibit angiogenesis and induce endothelial cells to
produce IL-2, MCP-1 and TGF-β1. Recombinant rat IL-17F is a non-glycosylated,
disulfide-linked homodimer.
Molecular Weight:
15.0/30.1 kDa (135/270 aa) dimer
Formulation:
Lyophilized from a sterile (0.2 micron) filtered aqueous solution containing 0.1% Trifluoroacetic Acid (TFA)
Purity:
≥ 95% by reducing and non-reducing SDS-PAGE
Endotoxin Level:
≤ 1 EU/μg by kinetic LAL analysis
Amino Acid Sequence:
MARRNPKVGL SALQKAGNCP PLEDNSVRVD IRIFNQNQGI SVPRDFQNRS SSPWD YNITR DPDRFPSEIA EAQCRHSGCI NAQGQEDGSM NSV PIQQEIL VLRREPQGCS NSFRLEKMLI KVGCTCVTPI VHHAA
Storage/Stability:
Store as supplied at -20°C to -80°C for up to 1 year.
