Recombinant Rat IL-2 Animal Free

Molecule:

IL-2

Synonyms:

Interleukin-2, aldesleukin, T cell growth factor

Species:

Rat

Cat. No.:

CRI146C-AF pdf (datasheet)

Quantity/Size:

1 mg

Price:

$3,520.00 / Special Price: $2,300.00 BUY

Description:

IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. IL-2/IL-2R signaling is required for T cell proliferation and other fundamental functions which are essential for the immune response. The receptor for IL-2 consists of three subunits (55 kDa IL2Rα, 75 kDa IL2Rβ, 64 kDa common gamma chain γc/IL2Rγ) that are present on the cell surface in varying preformed complexes. Recombinant rat IL-2 is a single non-glycosylated polypeptide chain containing 136 amino acids.

Entrez Symbol:

Il2

Uniprot ID:

P17108

Data PDF:

CRI146-AF

Source:

E. coli

Molecular Weight:

15.6 kDa

Physical State:

Lyophilized

Formulation:

Sterile-filtered aqueous solution containing 0.1% Trifluoroacetic acid (TFA).

Purity:

> 95 % by reducing and non-reducing SDS-PAGE

Biological Activity:

ED50 < 1 ng/ml, determined by a proliferation assay using murine CTLL-2 cells.

Specific Activity:

> 1 × 106 U/mg

Endotoxin Level:

≤1 EU/µg of protein by kinetic LAL analysis.

Amino Acid Sequence:

MAPTSSPAKE TQQHLEQLLL DLQVLLRGID NYKNLKLPMM LTFKFYLPKQ ATELKHLQCL ENELGALQRV LDLTQSKSFH LEDAGNFISN IRVTVVKLKG SENKFECQFD DEPATVVEFL RRWIAICQSI ISTMTQ

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.