Recombinant Rat Prolactin Animal Free

Molecule:

PRL

Synonyms:

Recombinant Rat Prolactin, PRL

Species:

Rat

Cat. No.:

CRR309C-AF pdf (datasheet)

Quantity/Size:

1 mg

Price:

$1,340.00 / Special Price: $1,020.00 BUY

Description:

Prolactin is a hormone that is produced and secreted by the pituitary gland. Prolactin acts in an endocrine, paracrine, and autocrine manner. The prolactin receptor (PRLR) is expressed on many cell types, including cells of the reproductive organs, central nervous system, and breast cancer. Prolactin signal transduction occurs via JAK kinase signaling pathways. The primary function of prolactin is to regulate lactation, but prolactin also plays functional roles in the immune system and during cell growth, apoptosis, and differentiation.

Manufactured without Animal-derived products, in an Animal Free facility.

Entrez Symbol:

Prl

Uniprot ID:

P01237

Data PDF:

CRR309-AF

Source:

E. coli

Molecular Weight:

Monomer, 22.7 kDa (198 aa)

Formulation:

Lyophilized from a sterile-filtered solution containing 20 mM sodium phosphate, pH 7.5

Purity:

≥ 95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Typical ED50 < 0.1 ng/ml, determined by dose-dependent proliferation of Nb2-11 cells

Endotoxin Level:

≤ 1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MLPVCSGGDC QTPLPELFDR VVMLSHYIHT LYTDMFIEFD KQYVQDREFI AKAINDCPTS SLATPEDKEQ AQKVPPEVLLNLILSLVHSW NDPLFQLITG LGGIHEAPDA IISRAKEIEE QNKRLLEGIE KIISQAYPEA KGNEIYLVWS QLPSLQGVDE ESKDLAFYNNIRCLRRDSHK VDNYLKFLRC QIVHKNNC

Storage/Stability:

Store as supplied at -20°C to -80°C for up to 1 year.