Recombinant Rat VEGF-165

Synonyms:

VEGF-A, VPF, glioma-derived endothelial cell mitogen

Cat. No.:

CRR310C pdf (datasheet)

Quantity/Size:

1.0 mg

Price:

$4,260.00 / Special Price: $2,800.00 BUY

Description:

Vascular endothelial growth factor-A (VEGF-A) is produced by a wide variety of cell types, including tumor and vascular cells. VEGF-A is a mediator of vascular growth, vascular permeability, and plays a role in stimulating vasodilation via nitric oxidedependent pathways. VEGF-A has several alternatively spliced isoforms, with VEGF-165 being the most abundant. The VEGF-165 isoform is a secreted protein that acts on receptors VEGFR-1 and VEGFR-2 to modulate endothelial cell proliferation and angiogenesis.

Uniprot ID:

P16612-2

Data PDF:

CRR310A

Source:

E. coli

Molecular Weight:

Dimer, 19.4/38.8 kDa (165/330 aa)

Physical State:

Lyophilized

Formulation:

Lyophilized from a sterile-filtered solution containing 10 mM sodium phosphate, pH 7.5

Purity:

≥95% by reducing and non-reducing SDS-PAGE

Biological Activity:

Activity determined by HUVEC proliferation assay

Endotoxin Level:

≤1 EU/µg by kinetic LAL analysis

Amino Acid Sequence:

MAPTTEGEQK AHEVVKFMDV YQRSYCRPIE TLVDIFQEYP DEIEYIFKPS CVPLMRCAGC CNDEALECVP TSESNVTMQI MRIKPHQSQH IGEMSFLQHS RCECRPKKDR TKPEKHCEPC SERRKHLFVQ DPQTCKCSCK NTDSRCKARQ LELNERTCRC DKPRR