S100B

S100 calcium binding protein B

Rhesus Macaque

CRS163B pdf (datasheet)

10 μg

$235.00 BUY

Recombinant Rhesus Macaque S100B is a single non-glycosylated polypeptide chain containing 91 amino acids

Background: S100B is glial-specific and is expressed primarily by astrocytes. Not all astrocytes express S100B. It has been shown that S100B is only expressed by a subtype of mature astrocytes that ensheath blood vessels and by NG2-expressing cells.
This protein may function in neurite extension, proliferation of melanoma cells, stimulation of Ca2+ fluxes, inhibition of PKC-mediated phosphorylation, astrocytosis and axonal proliferation, and inhibition of microtubule assembly. In the developing CNS it acts as a neurotrophic factor and neuronal survival protein.

CRS163

E. coli

~10.6 kDa

Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.

>97 % by SDS-PAGE and HPLC analyses.

Data Not Available.

Less than 1EU/μg of rRhS100B as determined by LAL method.

SELEKAMVAL IDVFHQYSGR EGDKHKLKKS ELKELINNEL SHFLEEIKEQ EVVDKVMETL DSDGDGECDF QEFMAFVAMV TTACHEFFEH E

Centrifuge vial prior to opening. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/ml. Stock solutions should be divided into working aliquots and stored at -80°C. Further dilutions should be made in appropriate buffered solutions.

The lyophilized protein is stable at 2-4°C, but should be kept desiccated at -20°C for long term storage. After reconstitution, the protein is stable for 1 week at 2-4°C. For long term storage, aliquot and freeze at -80°C. Avoid repeated freeze-thaw cycles.